FITC Anti-Mouse CD172a/SIRPα Antibody[P84] (E-AB-F1286C)

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Cell Markers

Size	Price	Qty
100Tests	$ 100.00	- +
50Tests	$ 65.00	- +
100Tests×2	$ 160.00	- +

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For research use only. Order now, ship in 3 days

Conjugation: FITC

Alternate Names	BIT, CD172 antigen-like family member A, P84, PTPNS1, SHPS-1, SIRPα
Clone	P84
Leadtime	Order now, ship in 3 days
Background	CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.
Abbre	CD172a
Swissprot	Q64314
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype	Rat IgG1, κ
Isotype Control	FITC Rat IgG1, κ Isotype Control[HRPN]
Applications	FCM
Research Areas	Cell Adhesion;Cell Biology;Immunology;Signal Transduction
Cellular Localization	Membrane
Form	Liquid
Concentration	5 μL/Test
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Storage	This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	24 months
Shipping	Ice bag